(27-29 April)

Day 1 : Course on adaptive designs

8h30-9h00 Registration
9h00-9h10 Welcome to BAYES2011
Bruno Boulanger, Arlenda
9h10-12h00 Adaptive design theory and practice (Part I)
Fabian Tibaldi, GSKBio
12h00-13h Lunch
13h10-17h00 Adaptive design theory and practice (Part II)
Fabian Tibaldi, GSKBio
Astrid Jullion, Arlenda

Day 2 : Presentation of Bayesian applications

Andy Grieve, ClinResearch
9h40-10h20 François Vandenhende, ClinBAY Bayesian methods for decision making in early phase: A few case examples
10h20-10h40 Coffee break
Wilbert van Duijnhoven, Business & Decision Bayesian methodology for an adaptive dose-finding trial with a bivariate binary response
11h20-12h Jonathan Jaeger, University of Louvain Bayesian ODE-penalized B-spline model
12h00-13h00 Lunch
13h00-13h40 Vincent Bremhorst, University of Bruxelles & UCB Pharma

Modeling the plasma concentration – time profile in a single rising dose study using the fractional polynomials approach.
13h40-14h20 Christel Faes, University of HasseltBayesian modeling of correlated and overdispersed data with application in a toxicity assay measuring gene damage
14h20-14h40 Coffee Break
14h40-15h20 Marina Savelieva, Novartis PharmaBayesian PKPD Modeling to Support Trial Design
15h20-17h00 Team workshop: How to set up an adaptive design?
Discussion with Alvaro Pereira and Denis Gossen, Aepodia


Day 3 : Presentation of Bayesian applications

9h00 -9h40 Bjorn Bornkamp, Novartis Pharma
Response Adaptive Dose-Finding under Model Uncertainty using the DoseFinding R package
9h40 -10h20 Pierre Lebrun, University of Liège & ArlendaValidation and routine use of Ligand-binding assays, a Bayesian opportunity
10h20-10h40 Coffee break
10h40-11h20 Joanna in ‘t Hout, MSDDose prediction using a Bayesian estimator on biomarker results
11h20-12h00 Thomasz Burzykowski, University of Hasselt & IDDIClinical trial design: Bayesian approach can be useful?
12h00 Tom Jacobs, UCBClosing remarks


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